解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:As a result of the reintroduction of malaria in the Republic of Korea (ROK) in 1993 and the threat to military and civilian populations, the Korea Military National Defense (MND) increased emphasis on vector control in 2012 at ROK Army (ROKA) installations located near the DMZ, while decreasing chemoprophyla...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1301-y
更新日期:2016-05-05 00:00:00
abstract:BACKGROUND:In Uganda, over half of under-five child mortality is attributed to three infectious diseases: malaria, pneumonia and diarrhoea. Integrated community case management (iCCM) trains village health workers (VHWs) to provide in-home diagnosis and treatment of these common childhood illnesses. For severely ill ch...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1300-z
更新日期:2016-04-29 00:00:00
abstract:BACKGROUND:The zoonotic malaria parasite Plasmodium knowlesi has become an emerging threat to South East Asian countries particular in Malaysia. A recent study from Sarawak (Malaysian Borneo) discovered two distinct normocyte binding protein xa (Pknbpxa) types of P. knowlesi. In the present study, the Pknbpxa of clinic...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1294-6
更新日期:2016-04-26 00:00:00
abstract:BACKGROUND:Malaria prevention has remained a critical area in the absence of efficacious vaccines against malaria. Drugs currently used as chemotherapeutics are also used in chemoprophylaxis increasing possible drug resistance. Asiatic acid is a natural phytochemical with oxidant, antioxidant and anti-inflammatory prop...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1278-6
更新日期:2016-04-21 00:00:00
abstract:BACKGROUND:Anopheles arabiensis is stereotypical of diverse vectors that mediate residual malaria transmission globally, because it can feed outdoors upon humans or cattle, or enter but then rapidly exit houses without fatal exposure to insecticidal nets or sprays. METHODS:Life histories of a well-characterized An. ar...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1280-z
更新日期:2016-04-19 00:00:00
abstract:BACKGROUND:Rosetting is associated with severe malaria and a primary cause of death in Plasmodium falciparum infections. Detailed understanding of this adhesive phenomenon may enable the development of new therapies interfering with rosette formation. For this, it is crucial to determine parameters such as rosetting an...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1243-4
更新日期:2016-04-18 00:00:00
abstract:BACKGROUND:Challenges persist in ensuring access to and optimal use of long-lasting, insecticidal bed nets (LLINs). Factors associated with ownership and use may differ depending on the history of malaria and prevention control efforts in a specific region. Understanding how the cultural and social-environmental contex...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1262-1
更新日期:2016-04-14 00:00:00
abstract:BACKGROUND:Anopheles nuneztovari sensu lato comprises cryptic species in northern South America, and the Brazilian populations encompass distinct genetic lineages within the Brazilian Amazon region. This study investigated, based on two molecular markers, whether these lineages might actually deserve species status. M...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1217-6
更新日期:2016-04-12 00:00:00
abstract:BACKGROUND:Despite declining prevalence of malaria in The Gambia, non-adherence to anti-malarial treatment still remains a challenge to control efforts. There is limited evidence on the socio-cultural factors that influence adherence to anti-malarial treatment in pregnancy. This study explored perceptions of malaria in...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12936-016-1255-0
更新日期:2016-04-11 00:00:00
abstract:BACKGROUND:Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation of the vaccine in Tanzania. This paper presents the views of stakeholders with regards to malaria vaccine in 12 Tanzanian ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1209-6
更新日期:2016-04-05 00:00:00
abstract:BACKGROUND:Over the past 15 years, mortality and morbidity due to malaria have been reduced substantially in sub-Saharan Africa and local elimination has been achieved in some settings. This study addresses the bio-ecology of larval and adult stages of malaria vectors, Plasmodium infection in Anopheles gambiae s.l. in ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1230-9
更新日期:2016-03-18 00:00:00
abstract:BACKGROUND:There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to determine the diagnostic accuracy of the NanoRam(®), a handheld Raman spectrometer (RS), to identify anti-malarial drugs. METHODS:In total, 289 anti-malarial d...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1212-y
更新日期:2016-03-15 00:00:00
abstract:BACKGROUND:Avian malaria vector competence studies are needed to understand more succinctly complex avian parasite-vector-relations. The lack of vector competence trials may be attributed to the difficulty of obtaining gametocytes for the majority of Plasmodium species and lineages. To conduct avian malaria infectivity...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1198-5
更新日期:2016-03-11 00:00:00
abstract:BACKGROUND:The effectiveness of vector control on malaria transmission by long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) depends on the vectors entering houses to blood feed and rest when people are inside houses. In the Solomon Islands, significant reductions in malaria have been achieved in...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1195-8
更新日期:2016-03-10 00:00:00
abstract::This article reports the changing pattern of US President's Malaria Initiative-funded IRS in sub-Saharan Africa between 2008 and 2015. IRS coverage in sub-Saharan Africa increased from <2 % of the at-risk population in 2005, to 11 % or 78 million people in 2010, mainly as a result of increased funding from PMI. The sc...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1201-1
更新日期:2016-03-08 00:00:00
abstract:BACKGROUND:With the dramatic increase in international travel among Chinese people, the risk of malaria importation from malaria-endemic regions threatens the achievement of the malaria elimination goal of China. METHODS:Epidemiological investigations of all imported malaria cases were conducted in nine provinces of C...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1188-7
更新日期:2016-03-05 00:00:00
abstract:BACKGROUND:The US FDA recently developed CD3+, a counterfeit detection tool that is based on sample illumination at specific wavelengths of light and visual comparison of suspect sample and packaging materials to an authentic sample. To test performance of the CD3+ in field conditions, a study was conducted in Ghana wh...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1180-2
更新日期:2016-02-25 00:00:00
abstract::The fight against malaria is increasingly threatened by failures in vector control due to growing insecticide resistance. This review examines the recent primary research that addresses the putative relationship between agricultural insecticide use and trends in insecticide resistance. To do so, descriptive evidence o...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-016-1162-4
更新日期:2016-02-19 00:00:00
abstract:BACKGROUND:Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all five Plasmodium parasites causing disease in humans. Although not included in the World Health Organization criteria for severe Plasmodium falciparum malaria, severe thrombocytopaenia has been increasingly men...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1150-8
更新日期:2016-02-19 00:00:00
abstract::This meeting report presents the key findings and discussion points of a 1-day meeting entitled 'Fake anti-malarials: start with the facts' held on 28th May 2015, in Geneva, Switzerland, to disseminate the findings of the artemisinin combination therapy consortium's drug quality programme. The teams purchased over 10,...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1096-x
更新日期:2016-02-13 00:00:00
abstract:BACKGROUND:Knowledge of the population genetics and transmission dynamics of Plasmodium vivax is crucial in predicting the emergence of drug resistance, relapse pattern and novel parasite phenotypes, all of which are relevant to the control of vivax infections. The aim of this study was to analyse changes in the geneti...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1136-6
更新日期:2016-02-09 00:00:00
abstract:BACKGROUND:Plasmodium vivax is very rarely seen in West Africa, although specific detection methods are not widely applied in the region, and it is now considered to be absent from North Africa. However, this parasite species has recently been reported to account for most malaria cases in Nouakchott, the capital of Mau...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1118-8
更新日期:2016-02-09 00:00:00
abstract:BACKGROUND:Malaria rapid diagnostic tests (RDTs) are assumed to be simple-to-use and mobile technologies that have the capacity to standardize parasitological diagnosis for malaria across a variety of clinical settings. In order to evaluate these tests, it is important to consider how such assumptions play out in pract...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1083-2
更新日期:2016-02-05 00:00:00
abstract:BACKGROUND:Chloroquine has been the treatment of choice for acute vivax malaria for more than 60 years. Malaria caused by Plasmodium vivax has recently shown resistance to chloroquine in some places. This study compared the efficacy and safety of fixed dose combination (FDC) of arterolane maleate and piperaquine phosph...
journal_title:Malaria journal
pub_type: 杂志文章,多中心研究
doi:10.1186/s12936-016-1084-1
更新日期:2016-01-27 00:00:00
abstract:BACKGROUND:Behaviour change communication (BCC) can improve malaria prevention and treatment behaviour. As a one of the activities under Myanmar Artemisinin Resistance Containment (MARC) programme, BCC have been conducting. This study aimed to evaluate the effectiveness of the behaviour change communication and communi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-1047-y
更新日期:2015-12-23 00:00:00
abstract::Malaria currently causes more harm to human beings than any other parasitic disease, and disproportionally affects low-income populations. The ethical issues raised by efforts to control or eliminate malaria have received little explicit analysis, in comparison with other major diseases of poverty. While some ethical ...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-015-1042-3
更新日期:2015-12-22 00:00:00
abstract:BACKGROUND:The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these natural products. Mal...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0999-2
更新日期:2015-12-18 00:00:00
abstract:BACKGROUND:An initial study of genetic diversity of Plasmodium falciparum in Asembo, western Kenya showed that the parasite maintained overall genetic stability 5 years after insecticide-treated bed net (ITN) introduction in 1997. This study investigates further the genetic diversity of P. falciparum 10 years after ini...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-1003-x
更新日期:2015-12-09 00:00:00
abstract:BACKGROUND:The development of insecticide resistance and the increased outdoor-biting behaviour of malaria vectors reduce the efficiency of indoor vector control methods. Attractive toxic sugar baits (ATSBs), a method targeting the sugar-feeding behaviours of vectors both indoors and outdoors, is a promising supplement...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-1012-9
更新日期:2015-12-08 00:00:00
abstract:BACKGROUND:This analysis examined how the proportion of children less than 5-years-old who slept under a bed net the previous night changed during and after a national long-lasting insecticidal net (LLIN) distribution campaign in Sierra Leone in November-December 2010. METHODS:A citywide cross-sectional study in 2010-...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0990-y
更新日期:2015-11-18 00:00:00
abstract:BACKGROUND:Colombia contributes a significant proportion of malaria cases in the Americas, which are predominantly rural. However, in the last 8 years ~ 10 % of the endemic municipalities have also reported urban and peri-urban malaria cases, a growing concern for health authorities. This study focused on the character...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0956-0
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:Malaria is a major public health problem in Uganda and the current policy recommends introduction of rapid diagnostic tests for malaria (RDTs) to facilitate effective case management. However, provision of RDTs in drug shops potentially raises a new set of issues, such as adherence to RDTs results, managemen...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12936-015-0979-6
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:Plasmodium ovale, considered the rarest of the malaria parasites of humans, consists of two morphologically identical but genetically distinct sympatric species, Plasmodium ovale curtisi and Plasmodium ovale wallikeri. These parasites resemble morphologically to Plasmodium vivax with which they also share a ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0985-8
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:The emergence of Plasmodium falciparum resistance to artemisinins threatens to undermine the effectiveness of artemisinin-based combination anti-malarial therapy. Developing suitable drugs to replace artemisinins requires the identification of new compounds that display rapid parasite killing kinetics. Howev...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0962-2
更新日期:2015-11-05 00:00:00
abstract:BACKGROUND:Antiplasmodial activities of angiotensin II and its analogues have been extensively investigated in Plasmodium gallinaceum and Plasmodium falciparum parasite species. Due to its vasoconstrictor property angiotensin II cannot be used as an anti-malarial drug. METHODS:This work presents the solid-phase synthe...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0974-y
更新日期:2015-11-04 00:00:00
abstract:BACKGROUND:Monitoring and evaluation of malaria programmes may require a combination of approaches to detect any effects of control. This is particularly true at lower transmission levels where detecting both infection and exposure to infection will provide additional evidence of any change. This paper describes use of...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0944-4
更新日期:2015-10-26 00:00:00
abstract:BACKGROUND:Malaria in Southeast Asia frequently clusters along international borders. For example, while most of Thailand is malaria free, the border region shared with Myanmar continues to have endemic malaria. This spatial pattern is the result of complex interactions between landscape, humans, mosquito vectors, and ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0921-y
更新日期:2015-10-05 00:00:00
abstract:BACKGROUND:The pro-inflammatory S100 calcium binding protein A8 (S100A8) is elevated in the serum of patients with Plasmodium falciparum malaria, but its function in Plasmodium vivax malaria is not yet clear. This function was investigated in P. vivax-infected patients in this study. METHODS:The level of S100A8 in the...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0855-4
更新日期:2015-10-05 00:00:00
abstract:BACKGROUND:The importance of the submicroscopic reservoir of Plasmodium infections for malaria elimination depends on its size, which is generally considered small in low transmission settings. The precise estimation of this reservoir requires more sensitive parasite detection methods. The prevalence of asymptomatic, s...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0906-x
更新日期:2015-09-30 00:00:00
abstract:BACKGROUND:The importance of net durability and the average useful life of a net is increasingly recognized as one of the critical factors that determine how often nets need to be replaced. A study to assess the effect of a net care and repair behaviour change communication (BCC) programme on net durability was conduct...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0899-5
更新日期:2015-09-22 00:00:00